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Atomic-level mapping of amorphous diabetes drug reveals hydrogen bonds as key to stability
Scientists at EPFL and AstraZeneca have developed a method to map the atomic-level structure of amorphous drugs, demonstrated on a GLP-1 receptor agonist candidate for diabetes and obesity treatment.
Scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have determined the atomic-level structure of a zinc-transporter protein, a molecular machine that regulates levels ...
For decades, scientists have known that motor proteins like kinesin-2 ferry vital cargo along microtubule "highways" inside cells. But how these molecular vehicles identify and bind to the right cargo ...
Crystallography is the science of analyzing the pattern produced by shining an X-ray beam through a material sample. A powder sample produces a different pattern than solid crystal. One longstanding ...
Knowledge of the atomic-level structures of materials is extremely important for correlating the properties and functions of material in any scientific discipline, including chemistry, biology, and ...
A joint research team from the Institute of Metal Research (IMR) of the Chinese Academy of Sciences and the Songshan Lake Materials Laboratory has achieved precise control and real-time observation of ...
When nucleic acids like DNA or RNA build up in a cell's cytoplasm, it sets off an alarm call for the immune system. Enzymes usually clear these nucleic acids before they cause an issue, but when these ...
High-entropy alloys (HEA) have a unique chemical composition that makes them strong, ductile, and resistant to wear-and-tear even at high temperatures. Yet this chemical composition also makes them ...
The inside of giant planets can reach pressures more than one million times the Earth's atmosphere. As a result of that intense pressure, materials can adopt unexpected structures and properties.
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