A recent study has revealed how Epstein-Barr virus (EBV) intensifies ulcerative colitis (UC), a debilitating inflammatory bowel disease. Researchers discovered that EBV infection triggers macrophage ...

This new article publication from Acta Pharmaceutica Sinica B, discusses how the use of a radiation-based immunogenic vaccine combined with a macrophage “checkpoint inhibitor” can boost innate and ...

Human colonic organoids (HCOs) made from pluripotent stem cells co-develop a variety of immune cells, including tissue-resident macrophages. And while they look like macrophages resident in the human ...

Inflammation in the gut can trigger a doom loop of sorts. The condition messes with the sensitive relationships between food, digestive acids, microbes and the immune system in ways that can promote ...

Ulcerative colitis (UC) is a chronic, relapsing disease that causes painful inflammation and ulcers in the colon. While its exact causes remain elusive, mounting evidence suggests that viral ...

A variant of the Aeromonas bacterium promoted colon inflammation in mice and was detected in stools and colon tissue from patients with ulcerative colitis (UC). Suspecting that gut-resident ...

(Nanowerk News) Engineers at the University of California San Diego have developed a pill that releases microscopic robots, or microrobots, into the colon to treat inflammatory bowel disease (IBD).

Epstein-Barr virus infection induces the upregulation of glycolysis in intestinal macrophages, which subsequently activates Gasdermin D, NLRP3, interleukin-1β, and interleukin-18 in macrophages within ...