An analysis of aging in Down syndrome and hypercholesterolemia mouse models has suggested that a Down syndrome-associated gene, DSCR-1, protects against abnormal vascularization of the cornea and ...

A 24-year-old woman presented to New England Eye Center upon referral from her outside ophthalmologist complaining of several years of light sensitivity, burning pain and blurred vision in both eyes.

Please provide your email address to receive an email when new articles are posted on . Scleritis is inflammation of the sclera and is predominantly autoimmune. Corneal thinning, astigmatism and ...

Scientists have identified a new genetic mutation that alters the function of cryopyrin and leads to a life-long periodic inflammation of the cornea, the transparent window of the human eye. Patients ...

<p>A) Actual image of corneal opacity in mice (arrow). Incidentally, this is the first model of corneal opacity caused by a genetic defect in the field of ophthalmology. </p> <p>B) Determining the ...

A corneal graft–keratoprosthesis is an artificial clear central corneal window surrounded by a human donor cornea. Implantation is generally done if a standard corneal transplant has failed, or when ...

The eye’s surface cornea is usually transparent, but infections or trauma can cause the cornea to become opaque, leading to sight loss or even complete blindness. Existing treatments for eye ...

Down syndrome and hypercholesterolemia mouse models suggest that the DSCR-1 gene protects against abnormal cornea vascularization and associated blindness by suppressing oxidized LDL cholesterol ...