Organoids—tiny, lab-grown 3D clusters of cells—are a useful tool for studying organ development, disease, and drug responses. These miniature organs-in-a-dish are powerful, but they’re not perfect: ...

Proof-of-concept trial in a single patient shows that cells can survive transplantation without immunosuppression ...

Adiponectin, a hormone secreted by adipose tissue, plays a doubly important role in preserving pancreatic function. In lean people, it protects beta cells, which make insulin, and in obese people, it ...

Researchers have developed a new organoid that mimics the human fetal pancreas, offering a clearer view of its early development. The researchers were able to recreate a complete structure that ...

Hans Clevers, PhD, has been working on organoids from the beginning. He was group leader for twenty years at the Hubrecht Institute and has been head of pharma research and early development (pRED) of ...

Scientists at the University of Wisconsin–Madison have uncovered a possible way to protect key cells in the pancreas that are targeted during the development of Type 1 diabetes. Type 1 diabetes is a ...

Researchers at UChicago have developed a nanoparticle system that can effectively deliver mRNA to insulin-producing cells, ...