Researchers have captured real-time "molecular movies" showing how an enzyme changes shape during catalysis. The study was published in Nature Communications.

It is well known in physics and chemistry that equal charges repel each other, while opposite charges attract. It was long assumed that this principle also applies when enzymes – the biological ...

Enzymology is the study of enzymes and enzyme-catalyzed reactions. Enzymes are biological catalysts that accelerate the rate of biological reactions. They can also perform multiple reactions ...

image: An one-pot chemoenzymatic cascade reaction to synthesize chiral alcohol was realized by using the highly active and selective enzyme-metal-single-atom hybrid as the catalyst. The ...

Reactions that can combine more than two molecular pieces in one go are a powerful way to build complexity quickly and save on costly isolation and purification. But the choreography for such a ...

Researchers defined the structure of a substrate-bound iron 2-oxoglutarate (Fe/2OG) enzyme to explore whether these enzymes could be used to create a wide array of molecules. They saw that Fe/2OG ...

Scientists achieve a novel biocatalytic reaction by repurposing natural enzymes with light, which could lead to valuable new chemical compounds. Engineering enzymes to perform reactions not found in ...