Researchers at Cardiff University have uncovered how a particularly severe form of DNA damage arises—shedding new light on ...

Scientists have uncovered how brewer’s yeast developed its unusually tiny centromeres, the DNA regions that guide chromosome separation during cell division. By studying related yeast species, ...

A study explains how broken DNA during cell division can trigger chromoanasynthesis when two repair pathways combine, causing ...

PHILADELPHIA – Human artificial chromosomes (HACs) capable of working within human cells could power advanced gene therapies, including those addressing some cancers, along with many laboratory ...

Cell division, the basic means by which genetic information is passed from generation to generation, involves tightly coordinated movements of a cell's DNA. This page describes the major phases of ...

The Y chromosome is among the smallest in the human body and carries the fewest genes. Researchers are paying renewed attention to its role in cancer—specifically, what happens when it vanishes.

Loss of the Y chromosome in aging men is widespread and increasingly linked to serious diseases, challenging assumptions that ...

The Telomere-to-Telomere (T2T) consortium, co-led by UC Santa Cruz Genomics Institute Associate Director Karen Miga and National Institutes of Health Genomics Research Institute Senior Investigator ...

For sexual reproduction to yield healthy offspring, newly generated oocytes—immature egg cells—must receive the correct amount of DNA after cell division. This process of segregating chromosomes ...

This important study demonstrates that a peri-nuclear actomyosin network, present in some types of human cells, facilitates kinetochore-spindle attachment of chromosomes in unfavorable locations - ...