The Pharmacology Consult column will periodically review basic principles of pharmacology and drug therapy management. Such reviews may be beneficial reminders of why recommendations for specific drug ...

In the manufacture of solid dosage forms, the rate at which the active pharmaceutical ingredient (API) is dissolved into solvents simulating the digestive tract fluids is determined with dissolution ...

Drug delivery as solid dosage forms is complex with a number of factors that can noticeably influence their therapeutic benefit. The drug must be stabilized in the tablet and at the same time be ...

Clin Drug Invest. 2005;25(7):435-443. Drug absorption and, therefore, the clinical effects of orally administered drugs strongly depend on their mode of transit through the gastrointestinal tract.

In this interview, Karl Box shows how particle drift analysis with flux techniques enhances oral drug absorption in pharmaceutical research. Can you tell us about Pion’s Rainbow Dynamic Dissolution ...

Advanced solutions are improving drug dissolution, absorption, and overall therapeutic performance. Drug solubility directly impacts bioavailability and absorption levels, and thus efficacy and safety ...

Advances in dissolution testing equipment are helping to meet user demands to a certain degree; however, more innovation in the space may be necessary for novel therapies, such as biologics.

What is the process of oral drug absorption, and how has the Fa equation evolved? Oral drug absorption begins with administering a drug product, followed by a rapid disintegration process. The drug ...

SUSTAINED-release products have been designed to contain in one dosage form the equivalent of several single doses of a drug, which is released to the body over an extended period. This slow release ...