An MRI-based cohort study shows HLA-B27–positive axial spondyloarthritis is linked to higher inflammation and distinct ...

This study involved 40 patients who met 3 criteria: HLA (human leukocyte antigen)-B27 positivity; less than 3 years of back pain that on history seemed inflammatory; and magnetic resonance imaging ...

Please provide your email address to receive an email when new articles are posted on . CHICAGO — In patients with inflammatory bowel disease, a “strong and consistent three-way interaction” was ...

Researchers have shown the endoplasmic reticulum (ER) stress pathway known as the unfolded protein response (UPR) is involved in the degradation of HLA-B27 heavy chain dimers. HLA-B27 is associated ...

Please provide your email address to receive an email when new articles are posted on . In patients with non-radiographic axial spondyloarthritis, MRI sacroiliitis and HLA-B27 positivity, but not ...

Axial disease is common and burdensome in patients with psoriatic arthritis (PsA). Human leukocyte antigen-B27 (HLA-B27) is a risk factor for axial PsA; treatment response by HLA-B27 status is ...

Human leukocyte antigen B27 (HLA-B27) positivity was associated with higher odds of non-remission in patients with juvenile idiopathic arthritis (JIA) at 18 years after disease onset, with men showing ...

The HLA-B27 genetic marker is known to be associated with increased risk for various arthropathies, including JIA. Whether the genetic marker's presence has prognostic value has been uncertain. In ...