The inflammatory response is a vital protective process, yet its dysregulation can lead to chronic conditions and tissue damage. Central to these processes is the regulation of nitric oxide (NO), a ...

A research team from the University of California, Irvine has revealed a previously unknown mechanism that triggers an inflammatory immune response in cells when their DNA is damaged. This discovery ...

A protein long understood to drive inflammation by producing nitric oxide has a second, previously unknown role - it physically binds to another key protein inside cells to directly modulate the ...

Whenever there is a wound or infection, the body produces an inflammatory response. This is the body's first line of defense, and macrophages—cells of the innate immune system—play a key role: first, ...

Researchers at the Garvan Institute of Medical Research have uncovered a critical mechanism driving inflammation in ...

Scientists have uncovered an unexpected mechanism by which the gut’s immune system maintains balance, challenging ...

Researchers have uncovered a previously unknown mechanism that regulates the immune response against parasites. During a parasitic infection, specific immune cells, known as virtual memory T cells ...

Black ginseng extract (4 μg/mL) could inhibit the expression of MMP-1 in human foreskin fibroblasts damaged by inflammation. Additionally, 0.1% BGE could not only inhibit the secretion of PGE2 in a ...

Cellular death within the infarcted core occurs rapidly due to energy depletion, resulting in the release of DAMPs such as HMGB1, ATP, and HSPs. These DAMPs engage pattern recognition receptors, ...

Scientists at The Wistar Institute and clinical researchers from ChristianaCare's Helen F. Graham Cancer Center & Research Institute have discovered a vulnerability in pancreatic cancer that could be ...