For the roughly 8.7 million people worldwide living with type 1 diabetes, daily life revolves around a problem their bodies ...

PSC-derived cells can reverse type 1 diabetes in mice and may overcome some of the hurdles faced by existing stem cell ...

Diabetes is the most common and serious chronic disease worldwide, characterized by insufficient insulin to maintain proper ...

Just as insulin therapy revolutionized life for people with type I diabetes (TID) a century ago, a new implant may one day do the same by tackling the disease’s biggest challenge—keeping transplanted ...

Our glycaemic balance is based on the ability of the pancreatic beta cells to detect glucose and secrete insulin to maintain our blood sugar levels. If these cells malfunction, the balance is broken, ...

Scientists in Sweden have taken a major step toward a potential cure for type 1 diabetes by developing a more reliable way to create insulin-producing cells from human stem cells. These lab-grown ...

In a proof of concept that may reshape the treatment landscape for insulin-dependent diabetes, scientists have demonstrated that human stomach cells can be reprogrammed to secrete insulin—potentially ...

In people with type 1 diabetes (T1D), the immune system shuts down the body's ability to make the hormone insulin, responsible for regulating blood sugar and providing cells with glucose to produce ...

Neurons like it tidy. Brain cells called glia help neurons perform at their best by cleaning up toxic cellular debris. But a diet high in sugar makes glia insulin resistant — which turns them into ...

For the roughly 1.6 million Americans living with type 1 diabetes, daily life revolves around a relentless calculation: check ...

Pancreatic islets from adult mice. On the left, islet composed of different types of endocrine cells. Right: pancreatic islet composed solely of beta cells. Our glycaemic balance is based on the ...