A pair of USC Stem Cell mouse studies detail how progenitor cells self-renew, differentiate, and aggregate into early kidney structures, offering insights for the creation of stem cell-based ...
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Kidney organoids uncover Hippo signaling pathway as a therapeutic target for nephronophthisis
Using human-induced pluripotent stem cell-derived kidney organoids, researchers from Science Tokyo uncovered how abnormal Hippo signaling drives fibrosis in nephronophthisis, a genetic kidney disorder ...
This is the longest-lived set of developing kidney organoids derived from tissue stem cells The kidney developed over a half a year, enabling real-time observation, gene isolation for birth defects ...
New research looked at how cancers arise in children who are predisposed to developing the childhood kidney cancer, Wilms tumor, which could help anticipate the development of tumors before they fully ...
TMAO (trimethylamine N-oxide) is a metabolite produced by gut bacteria and has emerged as a metabolite of interest due to its association with cardiovascular disease. Now, new findings from the ...
The global burden of chronic kidney disease (CKD) is rising, with more than 800 million people affected worldwide. Vascular diseases in patients with CKD are unique and grouped as uremic vascular ...
Xortx Therapeutics announces pioneering research on genome-wide pathogenic pathways in gout: Calgary, Alberta Saturday, January 3, 2026, 13:00 Hrs [IST] Xortx Therapeutics Inc., a ...
Vertex Pharmaceuticals VRTX initiated the late-stage portion of the phase II/III AMPLITUDE study evaluating inaxaplin (VX-147) in APOL1-mediated kidney disease (AMKD), a genetic disorder affecting ...
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