In neurodegenerative diseases, microglia can help or harm the brain. In the October 3 Journal of Clinical Investigation, scientists led by Ilia Baskakov at the University of Maryland School of ...

One of the biggest controversies in neuroscience dates back to 1906, when Camillo Golgi and Santiago Ramón y Cajal argued their opposing views on brain structure. 1 Golgi hypothesized that brain cells ...

In Alzheimer's disease, proteins like amyloid beta form clumps, known as plaques, that damage the brain. Subscribe to our newsletter for the latest sci-tech news updates. But in some people, immune ...

In a study published in Cell on April 7, a research team led by Prof. LI Hanjie from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences has revealed the presence ...

In chronic neurodegeneration associated with prion disease, reactive microglia adopt a highly mobile, neuron-by-neuron surveillance strategy, replacing homeostatic process-based monitoring with ...

Researchers have unveiled a critical mechanism that links cellular stress in the brain to the progression of Alzheimer's disease (AD). The study highlights microglia, the brain's primary immune cells, ...

A clearance mechanism involving microglia has been known to relieve neurons of toxic protein aggregates such as those associated with Alzheimer’s disease and Parkinson’s disease. Unfortunately, this ...

A sequence of stress signals among specialized clean-up cells in the brain could at last reveal why some immune responses can cause significant nerve degeneration that results in the loss of memory, ...

In Alzheimer's disease, proteins like amyloid beta form clumps, known as plaques, that damage the brain. But in some people, immune cells called microglia break down these proteins before they can ...