A genome-wide CRISPR study maps 331 genes essential for early brain development, identifying PEDS1 as a new ...

The enteric nervous system (ENS) is a sophisticated, autonomous network of neurons and glia embedded within the gastrointestinal tract, critical for regulating motility, secretion, and blood flow. The ...

An international research team identified hundreds of genes essential for the development of brain cells, including one gene ...

A new discovery by researchers challenges our current understanding of gastrulation, the most important stage of early embryonic development. When the zygote, or the fertilised egg, starts to develop, ...

Scientists have shed new light on how certain biological processes determine the development of neural cells. Their findings on a molecular 'bridge' complex demonstrate a new level of detail in the ...

By editing thousands of genes in mouse stem cells, the scientists identified a list of over 300 that are crucial for neural differentiation.

The neural crest is an extraordinary population of multipotent stem cells, unique to vertebrates, that plays a pivotal role in embryogenesis. Arising at the borders of the neural plate, these cells ...

Explore the function of genes involved in birth defects while developing skills in embryology, molecular biology, and developmental genomics. Intro text here... Project is Not Currently Available This ...

For decades, schizophrenia and bipolar disorder have been diagnosed from the outside in, through behavior, mood, and memory rather than the cells and circuits that go wrong. Now a new wave of brain ...

Scientists at the University of Southern California (USC) have developed an organoid model of the human brain that generates granule cells and Purkinje neurons—two major cell types found in the human ...

A Japanese research team has successfully reproduced the human neural circuit in vitro using multi-region miniature organs known as assembloids, which are derived from induced pluripotent stem (iPS) ...