The substantia nigra is a motor nucleus located in the basal ganglia of the midbrain. This brain structure contributes to the body's cognitive and motor functions by sending signals to initiate or ...

The intriguing finding that α-synuclein—a protein recently found to be mutated in some familial cases of Parkinson disease—and cytosolic dopamine interact to form adducts that stabilize a presumably ...

MRI imaging by contrast is safe, widely available, and doesn’t require patients to be injected with radioactive substances. However, using the imaging technique to examine the substantia nigra ...

About The Study: In this cross-sectional study of contact sports athletes with chronic traumatic encephalopathy (CTE), years of contact sports participation were associated with substantia nigra tau ...