Announcing a new publication for Acta Materia Medica journal. Proteins are essential macromolecules that perform functions according to their conformational dynamics. Studying the conformational ...
17hon MSN
New method reveals how mutations drive transthyretin amyloidosis and guides precision drug design
An international research team reveals new molecular mechanisms associated with pathogenic mutations in the protein ...
Morning Overview on MSN
AlphaFold rewired science, and 5 years later it’s still evolving
AlphaFold arrived as a technical moonshot that suddenly made protein structures feel like software rather than secrets of nature, and five years on it has rewired how laboratories plan experiments, ...
Researchers at Baylor College of Medicine have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called DeepMVP and ...
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1st-of-its-kind database reveals how DNA mutations 'destabilize' proteins, triggering genetic disease
Scientists have created a mega-database revealing how half a million different DNA mutations generate errors in proteins in humans. The researchers hope that the database will be used to develop new, ...
A study published today in Nature Structural & Molecular Biology is the first time researchers have shown evidence that a single drug, already licensed for medical use, can stabilize nearly all ...
From left to right, Mónica Centeno, Aina Prat, Juan Diego Gutiérrez, Susanna Balcells and Raquel Rabionet, members of the UB, the BUB, the IRSJD and the CIBERER. Mutations in the MAGEL2 gene, which ...
Of the more than 3 million people with breast cancer in the United Stated, about 10 percent carry an inherited mutation in their BRCA1 gene. In health, the gene is responsible for suppressing tumors.
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