Before a cell divides, its DNA is replicated so that each daughter cell inherits the same genetic information. The two copies, known as "sister chromatids," are held together by a ring-shaped protein ...

Half a century ago, scientists Jim Watson and Alexey Olovnikov independently realized that there was a problem with how our DNA gets copied. A quirk of linear DNA replication dictated that telomeres ...

The success of E. coli bacteria depends on their ability to multiply very rapidly by dividing into new cells. The bacteria can divide as quickly as they can make an entire new copy of their DNA while ...

A series of electron micrographs show the barrel-shaped helicase with several components of the replisome: a) helicase (grey) with Ctf4 (light blue), which is a recruitment factor for the ...

These cartoons show the old "textbook" view of the replisome, left, and the new view, right, revealed by electron micrograph images in the current study. Prior to this study, scientists believed the ...