A sweeping single-nucleus atlas reveals how human hearts lose cellular balance with age and points to PRDM16 as a potential molecular target for future cardiac aging research. Study: ...

Microtubules, part of heart muscle cells' internal "skeleton," help determine how the heart changes shape under stress, and a common signaling pathway called the ERK pathway acts as a key controller ...

A UC San Diego–led team has discovered that restoring a key cardiac protein called connexin‑43 in a mouse model can dramatically improve heart function and extend survival in several inherited forms ...

Every year, more than 200,000 people in Germany suffer a heart attack. This is caused by blocked coronary arteries. As a result, part of the heart muscle is no longer supplied with sufficient blood ...

A team at Massachusetts General Hospital uncovered that an immune defense protein, Resistin-like molecule gamma, attacks heart cells after a heart attack—literally punching holes in them. This ...

Over the course of evolution, the human heart has largely lost its ability to regenerate. Our distant ancestors were not afflicted by heart attacks—a condition that emerged primarily with modern ...

Jen Davis (left) and Bella Reichardt (right) conducting research in a lab for genetic engineering of heart fibroblasts.at the UW Medicine Institute for Stem Cell and Regeneration Medicine. Fibroblasts ...

For the first time, scientists have succeeded in artificially mimicking the ion signaling of heart muscle cells. To succeed, researchers at LiU have used organic electronics based on conductive ...

People who received an infusion of stem cells shortly after a heart attack were less likely to develop heart failure than those treated with standard care, according to the largest such trial to date.