In contrast to peripheral nerves, damaged axons in the mammalian brain and spinal cord rarely regenerate. Peripheral nerve injury stimulates neuronal expression of many genes that are not generally ...

For decades, numerous investigations have only focused on axon regeneration to restore function after traumatic spinal cord injury (SCI), as interrupted neuronal pathways have to be reconnected for ...

When the axons that extend from neurons break during a spinal cord injury, the result is often a lifelong loss of motor functioning, because vital connections from the brain to other body parts cannot ...

The regeneration of damaged neurons has been the ultimate goal for a large portion of neuroscience research. Understanding the underlying mechanisms that control neuronal growth is key to developing ...

Scientists at the National Institutes of Health (NIH) and the Indiana University School of Medicine report that increasing energy supply within injured spinal cord nerves in mice could help promote ...

The scientists conducted their experiments on isolated spinal cords removed from adult guinea pigs. Researchers fused the cut nerve fibers using a polymer called PEG. Electrical impulses were restored ...

Scientists have discovered that in addition to proteins, lipids are also necessary for guiding axons. The study shows how a phospholipid released by glial cells -- the cells in the nervous system that ...

Like power lines in an electrical grid, long wiry projections that grow outward from neurons - structures known as axons - form interconnected communication networks that run from the brain to all ...

Injections of a new drug may partially relieve paralyzing spinal cord injuries, based on indications from a study in rats. Every year, tens of thousands of people are paralyzed by spinal cord injuries ...

Capitalizing on the flexibility of tiny cells inside the body's smallest blood vessels may be a powerful spinal cord repair strategy, new research suggests. In mouse experiments, scientists introduced ...

Healing spinal cord damage is an incredibly difficult problem because neurons have to be reconnected in a precise fashion, and there are still many mysteries surrounding how this occurs. Now, ...