Targeting epigenetic modifiers and splicing regulators together may offer new acute myeloid leukemia treatment paths

Treating acute myeloid leukemia (AML) depends on knowing what goes wrong inside cells. A new study suggests that two genetic ...
Technology Networks

RNA Splicing Errors Disrupt Cellular Identity in Acute Myeloid Leukemia

New research provides a mechanistic map of how genetic mutations disrupt RNA splicing in acute myeloid leukemia.
Nature

RNA-rewriting candidate moves into the clinic

A growing list of editing tools can be used to make small changes to the genetic code, tweaking key nucleotides to address the underlying causes of diseases. But bigger edits are often needed, and ...
AZoLifeSciences on MSN

Dual genetic mutations drive RNA mis-splicing and leukemia progression

Treating acute myeloid leukemia (AML) depends on knowing what goes wrong inside cells. A new study suggests that two genetic ...