Corresponding Author: Zhenyu Yue, PhD, Director of The Center for Parkinson's Disease Neurobiology, Icahn School of Medicine at Mount Sinai; Bin Zhang, PhD, Director of the Mount Sinai Center for ...

Patients with Parkinson disease endure a progressive loss of neurons, especially dopaminergic, in the substantia nigra and other subcortical nuclei. Hallmarks of PD also include intracytoplasmic Lewy ...

The substantia nigra is a motor nucleus located in the basal ganglia of the midbrain. This brain structure contributes to the body's cognitive and motor functions by sending signals to initiate or ...

The death of dopaminergic neurons in the substantia nigra is the defining feature of Parkinson’s disease, but not all neurons in the region suffer this fate. Why do some wither while others survive ...

Northwestern University scientists have received two awards totaling nearly $18 million for Parkinson's disease research from The ASAP Collaborative Research Network, a program of the Aligning Science ...

Researchers at Mount Sinai have identified a unique neuron type that could explain vulnerability in Parkinson’s disease and thus help unravel the neuronal complexity of this disorder – hopefully ...

Parkinson’s disease (PD) is one of the fastest-growing neurodegenerative disorders worldwide, with increased longevity and aging populations contributing to this upward trajectory. PD has a profound ...

There may be a link between the SARS-CoV-2 infection of dopaminergic neurons and the long-term effects of COVID-19 symptoms like depression and brain fog, according to new research. Dopaminergic ...