Cell-adhesion molecules have a central role in synaptic plasticity, but their mechanisms of action have remained enigmatic. Ashley and colleagues have now identified the signalling machinery ...

Long-term forms of synaptic plasticity that may underlie learning and memory have been suggested to depend on changes in the number of synapses between presynaptic and postsynaptic neurons. Here we ...

Brains run on constant streams of chatter. The roughly 85 billion nerve cells in the human brain converse by sending messages via molecules called neurotransmitters. These chemical conversations allow ...

image: In Drosophila, octopamine signaling increases larval locomotor speed and synaptic bouton numbers at neuromuscular junctions under food deprivation conditions. We found that a glypican ...

Researchers have discovered that the cell adhesion protein IgSF11 determines the layer-specific synaptic connectivity of a distinct class of cortical interneurons. With its breathtaking views and ...

In a study supported by the National Institutes of Health (NIH), researchers revealed the structural underpinnings of memory formation across a broad network of neurons in the mouse brain. This work ...

"Since synaptic dysfunction is a key mechanism in AD, in this study, we quantified the changes in synaptic axonal boutons in AD mouse model in response to rTMS, comparing them to those in healthy mice ...

Researchers in Australia study effects of transcranial magnetic stimulation in mouse models of debilitating illness. 2-photon microscopy captures axonal segments in a living brain. Click for info.