Transplantation of bone marrow from mice with heart failure (TAC, meaning transverse aortic constriction) into healthy mice (control) led to cardiac dysfunction, as shown in this echocardiogram. The ...
Data from a preclinical study assessing Mission Therapeutics Ltd.’s clinical-stage USP30 inhibitor MTX-652, for the prevention of transverse aortic constriction (TAC)-induced cardiac hypertrophy and ...