A recombination between the short homologous regions of nucleotide sequences in the retroviral vector and packaging cell line has been thought to be a major cause of the production of ...

Viral vector service expansion empowers scientists by offering high-quality research reagents through on-demand AAV production from Addgene’s vast plasmid repository WATERTOWN, Mass., January 10, 2025 ...

Adenoviral vectors (AdVs) have been regarded as one of the most efficient gene delivery vehicles in vivo, and have been used in human gene therapy protocols.1 2 Their virions are relatively stable, ...

WILMINGTON, Mass.--(BUSINESS WIRE)--Charles River Laboratories International, Inc. (NYSE: CRL) today announced the launch of its off-the-shelf lentiviral vector (LVV) packaging plasmids, providing a ...

Lentiviral vectors are versatile gene delivery tools, capable of transducing a wide range of cell types. However, producing large volumes of high-quality lentiviruses can present several challenges.

Charles River’s off-the-shelf lentiviral vector packaging plasmids are intended for use with cell and gene therapies. Charles River Laboratories, a pharmaceutical company specializing in cell and gene ...