β-Lactamases represent a broad family of enzymes that undermine the efficacy of β-lactam antibiotics by hydrolysing the characteristic β-lactam ring. Their diversity arises from multiple evolutionary ...
For bloodstream infections caused by chromosomal AmpC β-lactamase-producing strains, cefepime may be an appropriate carbapenem-sparing treatment option. Cefepime is supported as an alternative to ...
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