Interactions between engineered nanoparticles and biological membranes underlie many emerging diagnostic and therapeutic strategies. Nanoparticles can be designed with tailored size, shape, surface ...

Using a powerful single-molecule imaging method they developed, a Broad Institute research team has unveiled a dynamic view ...

Cancer cells have softer membranes than healthy cells. New nanoparticles exploit this physical difference to fuse selectively with tumors and deliver mRNA therapy with minimal off-target effects. That ...

Aim: This study examines the absolute quantification of particle uptake into cells. Methods: We developed a novel method to analyze stacks of confocal fluorescence images of single cells interacting ...

Researchers from Xi’an Jiaotong-Liverpool University (XJTLU) in China have developed a streamlined process that makes it easier to produce tiny therapeutic particles released by cells, called exosomes ...

Recent technological advances are fueling the development of cutting-edge technologies that can monitor and control physiological processes with high precision. These include devices that could ...

An enduring challenge for the commercialization of genetic therapies is delivering the therapeutic molecules to the proper destination within the body. Viruses are natural delivery systems for nucleic ...

In a demonstration that could help pave the way for gene therapies with fewer side effects, several human cell types have been genetically modified with protein nanoparticles designed at University of ...

Nanoplastics are tiny plastic particles measured at the nanometer scale, which may be capable of crossing the blood-brain ...

While this protects the brain from external threats, it also presents a major challenge for treating neurological diseases, as many potentially therapeutic compounds are unable to cross. One potential ...

Antimicrobial nanoparticles are materials with exceptional antimicrobial properties, capable of controlling bacterial, viral, and fungal infections. Thanks to their unique physicochemical attributes, ...