The skin is presumably the largest and one of the most versatile body organs. By providing a physical barrier, it protects our body from environmental assaults. Melanin - a natural pigment produced by ...

Researchers from Doshisha University suggest that a transcription factor “Nrf3” coordinates the melanogenesis pathway in response to forskolin or αMSH via macropinocytosis and autophagy. They also ...

Since its introduction more than ten years ago, CRISPR technology has been used in a remarkable range of applications from biomedicine to food production. Now, a team of scientists from Stanford ...

Melanin is a major pigment present in vertebrates. The type and rate of melanin synthesised determines both skin and hair colour. Melanin is a light absorbing polymer derived from the essential amino ...

Image 3. The efficacy of melanogenesis inhibition on mouse dorsal skin. a) Optical images of mice dorsal skin after photo-treatment for 20 days. b) Histological analysis of mice dorsal skin. Less ...

A novel application for a compound called ML233 has shown promising results for inhibiting melanin production, offering potential new strategies for the treatment of pigment-related skin conditions ...