A team of researchers has uncovered a previously unrecognized role of mitochondrial protein synthesis in the maintenance of intracellular iron distribution. Disruption of this process was found to ...

Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by differences in how people interact or ...

Nucleotide synthesis—the production of the basic components of DNA and RNA—is essential for cell growth and division. In most animal cells, this process depends closely on properly functioning ...

Aging-related diseases, including cancer, cardiovascular disorders and type 2 diabetes, are associated with defects in protein synthesis and folding. Previous studies have shown that protein ...

In a new study, researchers from Japan demonstrate that COX7RP, a mitochondrial protein, may play a key role in enhancing mitochondrial energy efficiency, leading not only to longer lifespans but also ...

In a recent study published in Nature, researchers from the United States of America investigated how cells separate competing metabolic pathways within mitochondria, namely oxidative phosphorylation ...

A novel study uncovers how a subtle chemical tweak transforms the naturally occurring phytotoxin into a powerful molecular glue, 12-deoxyfusicoccin (12-dFC), that locks 14-3-3 proteins onto the ...

A defect in mitochondrial tRNA modification impairs the proper formation of mitochondrial OXPHOS complexes, which results in iron transmigration from mitochondria to cytosol. Excess cytosolic iron ...