HLA-B27 - Wikipedia
Human leukocyte antigen (HLA) B27 (subtypes B*2701-2759) [1] is a class I surface molecule encoded by the B locus in the major histocompatibility complex (MHC) on chromosome 6 and presents …
HLA-B27 Gene and Arthritis | Arthritis Foundation
This article explains what the HLA-B27 gene is, how it relates to certain forms of arthritis, and what the science really shows. The complex ideas are broken down into simple language you can follow.
What Is the HLA-B27 Test for and What Do the Results Mean?
Dec 14, 2025 · Clarify the meaning of the HLA-B27 test. Learn how this immune marker assesses risk for chronic inflammatory and rheumatic conditions.
HLA-B27 antigen: MedlinePlus Medical Encyclopedia
Apr 1, 2025 · The protein is called human leukocyte antigen B27 (HLA-B27). Human leukocyte antigens (HLAs) are proteins that help the body's immune system tell the difference between its own cells and …
Positive HLA-B27 and arthritis - Connected Rheumatology
Dec 9, 2024 · Learn how the HLA-B27 gene impacts your risk for Ankylosing Spondylitis and arthritis. Understand your test results and what they mean for your health.
HLA B27 Test - Purpose, Results, Normal Range, and more
The HLA B27 test is a medical diagnostic test used to determine the presence of the HLA B27 antigen on the surface of white blood cells. This genetic marker is associated with a range of autoimmune …
HLA-B27 Syndromes: Overview, Pathophysiology, Clinical ... - Medscape
Oct 1, 2024 · The first human leukocyte antigen (HLA) haplotype association with inflammatory disease was discovered in 1972, correlating HLA-B27 with ankylosing spondylitis. This remains one of the...
Human Leukocyte Antigen B27 (HLA-B27) - Healthline
Nov 13, 2018 · Although most HLAs protect your body from harm, HLA-B27 is a specific type of protein that contributes to immune system dysfunction. The presence of HLA-B27 on your white blood cells …
HLA-B27 Antigen - University of Rochester Medical Center
What is this test? This test looks for HLA-B27, which are proteins called antigens. These are found on the surface of white blood cells that are fighting infection. If you have HLA-B27, you may have an …
Understanding HLA-B27 Positive: Symptoms and Management
In this comprehensive guide, we'll explore what it means to be HLA-B27 positive, its relationship with various health conditions, and how to approach testing and management strategies.