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  1. IRF3 - Wikipedia

    IRF3 was originally discovered as a homolog of IRF1 and IRF2. IRF3 has been further characterized and shown to contain several functional domains including a nuclear export …

  2. IRF3 in viral infections: more than just triggering the ...

    Sep 2, 2025 · Interferon regulatory factor 3 (IRF3) is the first transcription factor activating the expression of type I interferons (IFN-I).

  3. IRF3 Gene - GeneCards | IRF3 Protein | IRF3 Antibody

    Nov 13, 2025 · IRF3 (Interferon Regulatory Factor 3) is a Protein Coding gene. Diseases associated with IRF3 include Encephalopathy, Acute, Infection-Induced 7and Primary …

  4. IRF3 interferon regulatory factor 3 [Homo sapiens (human ...

    May 3, 2025 · Gene target information for IRF3 - interferon regulatory factor 3 (human). Find diseases associated with this biological target and compounds tested against it in bioassay …

  5. Interferon regulatory factor 3 (IRF3) - Abcam

    IRF3 regulates the expression of interferons (IFNs) and IFN-stimulated genes (ISG). The interferon regulatory factor family includes 9 members. IRF3 is a key transcription factor in the …

  6. Regulation of IRF3 activation in human antiviral signaling ...

    Jun 1, 2022 · This review will provide insights into the antiviral IRF3 signaling pathways while focusing on the recent updates of the IRF3-activation complex components.

  7. Entry - *603734 - INTERFERON REGULATORY FACTOR 3; IRF3

    The IRF3 gene encodes interferon regulatory factor-3, a transcription factor that activates transcription of interferon (see, e.g., IFNB1, 147640)-related genes that have antiviral activity …