Inflammasomes are cytosolic multiprotein complexes of the innate immune system responsible for the activation of inflammatory responses and cell death. [1][2] They are formed as a result of …

Jan 5, 2024 · Each inflammasome complex has three major components: an upstream sensor molecule that is connected to a downstream effector protein such as caspase-1 through the …

Jul 25, 2025 · Inflammasomes are complex molecular structures found inside the body’s cells, acting as a part of the innate immune system. They serve as internal sensors, monitoring for …

Oct 9, 2023 · Inflammasomes are a group of protein complex located in cytoplasm and assemble in response to a wide variety of pathogen-associated molecule patterns, damage-associated …

Aug 13, 2025 · What is an inflammasome? An inflammasome is a cytosolic multiprotein complex that plays a critical role in the innate immune response by detecting pathogens and cellular …

Inflammasome is defined as a multiprotein complex that plays a crucial role in the activation of inflammatory responses and cell death, particularly through mechanisms such as pyroptosis, …

Inflammasomes are assembled by innate immune sensors that cells employ to detect a range of danger signals and respond with pro‐inflammatory signalling.

Jul 3, 2023 · In the past decade, our understanding of inflammasome biology and activation mechanisms has greatly progressed. We therefore provide an up-to-date overview of the …

Inflammasomes are a group of protein complex located in cytoplasm and assemble in response to a wide variety of pathogen-associated molecule patterns, damage-associated molecule …

Jun 29, 2015 · The inflammasomes are innate immune system receptors and sensors that regulate the activation of caspase-1 and induce inflammation in response to infectious …