Jul 1, 2025 · Mitral annular calcification (MAC) is a degenerative process that causes calcium deposits along the mitral annulus. The pathophysiological mechanisms contributing to the …

Feb 3, 2015 · Mitral annular calcification is a chronic process in which there is deposition of calcium in the mitral valve annulus. The mitral annulus is typically flexible. In mitral annular …

Mitral annular calcification (MAC) is a multifactorial chronic degenerative process in which calcium with lipid is deposited (calcified) in the annular fibrosa ring of the heart's mitral valve.

New techniques and technology for the treatment of severe mitral annular calcification.

Jun 30, 2025 · In advanced cases, MAC may cause significant obstruction of left ventricular (LV) inflow and symptomatic mitral stenosis. MAC is also associated with atherosclerotic …

Dec 21, 2025 · Mitral annular calcification refers to the deposition of calcium (along with lipid) in the annular fibrosa of the mitral valve.

May 24, 2023 · Mitral annular calcification (MAC) is a chronic degenerative process of the mitral valve ring; it was first described in 1908 by Bonninger as associated with complete heart block.

Sep 25, 2023 · The authors review the clinical and anatomical features of MAC that are favorable (green light), challenging (yellow light), or prohibitive (red light) for surgical or transcatheter …

Understanding how mitral annular calcification is assessed and how it may influence the outcomes of treatment options.

Mitral Annular Calcification occurs when calcium deposits accumulate in the fibrous ring around the mitral valve in the heart. Several factors can contribute to this condition, including aging, …