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  1. Phosphatidylinositol 3-phosphate - Wikipedia

    Phosphatidylinositol 3-phosphate (PI3P) is a phospholipid found in cell membranes that helps to recruit a range of proteins, many of which are involved in protein trafficking, to the membranes.

  2. Phosphatidylinositol-3-phosphate in the regulation of autophagy ...

    Phosphatidylinositol-3-phosphate (PI3P) is a key player in membrane dynamics and trafficking regulation. Most PI3P is associated with endosomal membranes and with the autophagosome …

  3. Phosphatidylinositol 3-phosphate regulates iron transport via PI3P ...

    Jul 24, 2023 · We identified the PI3P-binding protein CgPil1 through PI3P interactome analysis and showed how CgPil1 aids in CgFtr1 retention at the PM based on the environmental iron abundance.

  4. PI3KC2α-dependent and VPS34-independent generation of PI3P ... - Nature

    Jan 15, 2020 · Phosphatidylinositol-3-phosphate (PI3P), a crucial lipid in membrane dynamics, is known to be essential in this context.

  5. Phosphatidylinositol 3-Phosphate - an overview - ScienceDirect

    Phosphatidylinositol 3-phosphate [PtdIns (3)P], a phospholipid produced by PI 3-kinases in early endosomes and multivesicular bodies, often serves as a marker of endosomal membranes.

  6. Phosphoinositide Lipid Signaling | The Emr Lab

    Mutations in PIP metabolic genes are closely linked to serious human diseases including cancer. Specific PIP lipids are enriched in specific subcellular compartments, PI3P is enriched on …

  7. Phosphatidylinositol (3,4,5)-trisphosphate - Wikipedia

    Phosphatidylinositol (3,4,5)-trisphosphate (PtdIns (3,4,5)P3), abbreviated PIP3, is the product of the class I phosphoinositide 3-kinases ' (PI 3-kinases) phosphorylation of phosphatidylinositol (4,5) …

  8. PI3P-dependent regulation of cell size and autophagy by ...

    Jun 14, 2023 · In this study, we report a role for PIP4K in regulating PI3P levels in Drosophila. Loss-of-function mutants of the only Drosophila PIP4K gene show reduced cell size in salivary glands.

  9. Exploring the Role of PI3P in Platelets: Insights from a Novel ... - MDPI

    Mar 24, 2023 · Our study demonstrates the presence of a pool of phosphatidylinositol 3-monophosphate (PI3P) in the outer leaflet of the plasma membrane of resting human and mouse platelets. This pool …