
Phosphatidylinositol 3-phosphate - Wikipedia
Phosphatidylinositol 3-phosphate (PI3P) is a phospholipid found in cell membranes that helps to recruit a range of proteins, many of which are involved in protein trafficking, to the membranes.
Phosphatidylinositol-3-phosphate in the regulation of autophagy ...
Phosphatidylinositol-3-phosphate (PI3P) is a key player in membrane dynamics and trafficking regulation. Most PI3P is associated with endosomal membranes and with the autophagosome …
Phosphatidylinositol 3-phosphate regulates iron transport via PI3P ...
Jul 24, 2023 · We identified the PI3P-binding protein CgPil1 through PI3P interactome analysis and showed how CgPil1 aids in CgFtr1 retention at the PM based on the environmental iron abundance.
PI3KC2α-dependent and VPS34-independent generation of PI3P ... - Nature
Jan 15, 2020 · Phosphatidylinositol-3-phosphate (PI3P), a crucial lipid in membrane dynamics, is known to be essential in this context.
Phosphatidylinositol 3-Phosphate - an overview - ScienceDirect
Phosphatidylinositol 3-phosphate [PtdIns (3)P], a phospholipid produced by PI 3-kinases in early endosomes and multivesicular bodies, often serves as a marker of endosomal membranes.
Phosphoinositide Lipid Signaling | The Emr Lab
Mutations in PIP metabolic genes are closely linked to serious human diseases including cancer. Specific PIP lipids are enriched in specific subcellular compartments, PI3P is enriched on …
Phosphatidylinositol (3,4,5)-trisphosphate - Wikipedia
Phosphatidylinositol (3,4,5)-trisphosphate (PtdIns (3,4,5)P3), abbreviated PIP3, is the product of the class I phosphoinositide 3-kinases ' (PI 3-kinases) phosphorylation of phosphatidylinositol (4,5) …
PI3P-dependent regulation of cell size and autophagy by ...
Jun 14, 2023 · In this study, we report a role for PIP4K in regulating PI3P levels in Drosophila. Loss-of-function mutants of the only Drosophila PIP4K gene show reduced cell size in salivary glands.
Exploring the Role of PI3P in Platelets: Insights from a Novel ... - MDPI
Mar 24, 2023 · Our study demonstrates the presence of a pool of phosphatidylinositol 3-monophosphate (PI3P) in the outer leaflet of the plasma membrane of resting human and mouse platelets. This pool …