Pigment epithelium-derived factor (PEDF) also known as serpin F1 (SERPINF1), is a multifunctional secreted protein that has anti-angiogenic, anti- tumorigenic, and neurotrophic …

Pigment epithelium-derived factor (PEDF) is defined as an endogenously produced 50 kDa glycoprotein that exhibits neurotrophic, neuroprotective, cell differentiating, antitumour, and …

Pigment epithelium-derived factor (PEDF) is a versatile protein with potent effects against various cancers. It hinders cancer initiation and spread. This review highlights some of the molecular …

Jul 21, 2025 · This review highlights recent findings on the potent anti-angiogenic serpin protein, pigment epithelium-derived factor (PEDF) as it relates to metabolic disease, diabetes, …

Aug 1, 2003 · Pigment epithelium-derived factor (PEDF) is a molecule with neurotrophic, neuroprotective and antiangiogenic properties. It is structurally related to the serpin family of …

Jun 18, 2025 · Pigment Epithelium-Derived Factor, or PEDF, is a protein naturally produced by the human body. It belongs to a family of proteins called serpins and is composed of 418 …

Pigment epithelium-derived factor (PEDF; encoded by SERPINF1 and also known as EPC1 and caspin), is a serpin that has multiple biological actions. The era of PEDF research began …

Sep 1, 2022 · Pigment epithelium-derived factor (PEDF), a potent inhibitor of angiogenesis, exerts antiangiogenic effects without affecting the structure and function of normal blood vessels. …

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Mar 14, 2013 · PEDF is a potent inhibitor of angiogenesis through pro-apoptotic effects on endothelial cells. It can also inhibit endothelial cell migration, endothelial tube formation, vessel …